Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411494 | 0.92 | HTR1F (0.41) | HTR1FHTR6MEN1NPC1MAPT | |
| SCHEMBL7411529 | 0.90 | HTR1F (0.43) | HTR1FHTR6 | |
| SCHEMBL7417232 | 0.82 | BRD4 (0.41) | HTR1FMAPK1MEN1MAPTCASP3 | |
| SCHEMBL7409286 | 0.82 | HTR1F (0.37) | HTR1FHTR6KMT2ACHRM3 | |
| SCHEMBL7407854 | 0.81 | CHRM3 (0.44) | HTR1FCHRM3 | |
| SCHEMBL7410521 | 0.81 | HTR1F (0.41) | HTR1FHTR6CHRM3 | |
| Hydrochloric Acid SCHEMBL7407442 | 0.80 | HTR1F (0.41) | HTR1FHTR6CHRM3 | |
| SCHEMBL7412099 | 0.78 | CHRM3 (0.40) | HTR1FCHRM3 | |
| SCHEMBL7409296 | 0.77 | HTR6 (0.41) | HTR1FHTR6MAPT | |
| Hydrochloric Acid SCHEMBL7407346 | 0.77 | ALDH1A1 (0.44) | HTR1FMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |