Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 8/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.33 |
| ▸ | CPT1A | P50416 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741966 | 1.00 | AKT1 (0.36) | AKT1GRIA1CACNG8PADI4SMYD3 | |
| SCHEMBL741416 | 0.93 | CFD (0.36) | AKT1PADI4SMYD3CDK2CPT2 | |
| SCHEMBL741417 | 0.93 | CFD (0.36) | AKT1PADI4SMYD3CDK2CPT2 | |
| SCHEMBL741160 | 0.91 | BTK (0.31) | BTKCFDNPY1R | |
| SCHEMBL741161 | 0.91 | BTK (0.31) | BTKCFDNPY1R | |
| SCHEMBL742030 | 0.90 | NSD2 (0.36) | PADI4 | |
| SCHEMBL742029 | 0.90 | NSD2 (0.36) | PADI4 | |
| SCHEMBL741987 | 0.89 | SMYD3 (0.35) | PADI4SMYD3BTKCFDNPY1R | |
| SCHEMBL741986 | 0.89 | SMYD3 (0.35) | PADI4SMYD3BTKCFDNPY1R | |
| SCHEMBL740294 | 0.88 | CFD (0.37) | PADI4SMYD3CPT2CPT1ACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | claimed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |