Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977952 | 0.87 | LMNA (0.45) | MAPK1LMNAL3MBTL1NPY1RMC4R | |
| SCHEMBL4443935 | 0.87 | HCAR3 (0.41) | MAPK1LMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL7412611 | 0.87 | HCAR3 (0.41) | MAPK1LMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL7416176 | 0.83 | BCL2 (0.43) | MAPK1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4440995 | 0.83 | BCL2 (0.43) | MAPK1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL7413629 | 0.78 | NPC1 (0.43) | MAPK1LMNAL3MBTL1NPY1RMC4R | |
| SCHEMBL4449996 | 0.74 | ALOX15 (0.38) | L3MBTL1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7413823 | 0.74 | ALOX15 (0.38) | L3MBTL1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL13099959 | 0.74 | HPGD (0.43) | MAPK1LMNAMEN1KMT2AHPGD | |
| SCHEMBL7979459 | 0.73 | HCAR3 (0.47) | MAPK1LMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |