Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449996 | 1.00 | ALOX15 (0.38) | ALOX15PRKCIAAK1GAARAB9A | |
| SCHEMBL7981483 | 0.86 | PRKCI (0.39) | PRKCIGAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7412611 | 0.84 | HCAR3 (0.41) | GAARAB9ANPC1NPSR1HTT | |
| SCHEMBL4443935 | 0.84 | HCAR3 (0.41) | GAARAB9ANPC1NPSR1HTT | |
| SCHEMBL7100641 | 0.83 | AAK1 (0.38) | ALOX15PRKCIAAK1RAB9ANPC1 | |
| SCHEMBL13099959 | 0.76 | HPGD (0.43) | GAASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL7411883 | 0.75 | AAK1 (0.41) | PRKCIAAK1 | |
| SCHEMBL7411897 | 0.74 | MAPK1 (0.44) | GAANPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7476265 | 0.71 | ALOX15 (0.36) | ALOX15PRKCIRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7979459 | 0.70 | HCAR3 (0.47) | RAB9ANPC1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |