Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411897 | 0.87 | MAPK1 (0.44) | LMNAMAPK1L3MBTL1NPY1RMC4R | |
| SCHEMBL7979459 | 0.85 | HCAR3 (0.47) | LMNAMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL4443935 | 0.73 | HCAR3 (0.41) | LMNAMAPK1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL7981483 | 0.72 | PRKCI (0.39) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6821981 | 0.72 | VCAM1 (0.53) | LMNAMAPK1VCAM1ALDH1A1MEN1 | |
| SCHEMBL732303 | 0.71 | THRB (0.49) | LMNAMAPK1VCAM1ALDH1A1MEN1 | |
| SCHEMBL7416176 | 0.71 | BCL2 (0.43) | LMNAMAPK1VCAM1ALDH1A1MEN1 | |
| SCHEMBL4440995 | 0.71 | BCL2 (0.43) | LMNAMAPK1VCAM1ALDH1A1MEN1 | |
| SCHEMBL12591651 | 0.70 | VCAM1 (0.53) | LMNAMAPK1VCAM1ALDH1A1MEN1 | |
| SCHEMBL4442693 | 0.70 | VCAM1 (0.50) | LMNAMAPK1VCAM1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |