SCHEMBL74126

SCHEMBL74126

Cc1ccc(N(c2ccc(-c3ccc(N(c4ccc(C)cc4)c4ccc(-c5ccc6sc7ccccc7c6c5)cc4)cc3)cc2)c2ccc(-c3ccc4sc5ccccc5c4c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.42
ALDH1A1 P00352 4/20 0.37
MAPT P10636 4/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.37
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
GABRA4 P48169 1/20 0.36
GABRE P78334 1/20 0.36
GABRA6 Q16445 1/20 0.36
GABRG1 Q8N1C3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12925374 1.00 GPR3 (0.42) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL17660126 0.94 GPR3 (0.38) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL29362959 0.94 GPR3 (0.42) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL19447683 0.94 GPR3 (0.42) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL15946726 0.94 GPR3 (0.42) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL18400174 0.92 ROCK1 (0.40) ALDH1A1MAPTRAB9ASMN1; SMN2HPGD
SCHEMBL6374195 0.92 GPR3 (0.50) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL22760590 0.92 GPR3 (0.38) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL18389471 0.91 GPR3 (0.40) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL21579611 0.91 GPR3 (0.40) GPR3ALDH1A1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185333-B1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORP (US) 2023-09-06 EP disclosed
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-10446761-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-10-15 US disclosed
US-20190081245-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-03-14 US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 US disclosed
US-9444053-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-09-13 US disclosed
US-20140159006-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-06-12 US disclosed
US-20140159006-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-06-12 US disclosed
US-8623522-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-07 US disclosed
US-8623522-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-07 US disclosed
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 GPR3 3499/4885ALDH1A1 351/4885MAPT 409/4885
US-10446761-B2 Aromatic amine derivative and electroluminescence device using the same EML4, DDC, TYR GPR3 3378/4885ALDH1A1 470/4885MAPT 376/4885
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same ALK, ALKBH3, ACVRL1 GPR3 3038/4885ALDH1A1 177/4885MAPT 966/4885
US-20190081245-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME EML4, DDC, TYR GPR3 3378/4885ALDH1A1 470/4885MAPT 376/4885
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 GPR3 3499/4885ALDH1A1 351/4885MAPT 409/4885
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 GPR3 3499/4885ALDH1A1 351/4885MAPT 409/4885
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 GPR3 3499/4885ALDH1A1 351/4885MAPT 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.