Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415639 | 0.85 | F2 (0.49) | PPARGNPC1RAB9AHDAC6 | |
| SCHEMBL7968222 | 0.79 | ALDH1A1 (0.38) | MAPTKDM4EBRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8028429 | 0.70 | F2 (0.47) | — | |
| SCHEMBL7377767 | 0.70 | ALDH1A1 (0.53) | PPARGNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7383468 | 0.69 | RAB9A (0.58) | PPARGNPC1RAB9AHDAC6MAPT | |
| SCHEMBL6778595 | 0.67 | PPARG (0.52) | PPARGNPC1RAB9AALDH1A1CYP19A1 | |
| SCHEMBL7378592 | 0.65 | PPARG (0.51) | PPARGNPC1RAB9AHDAC6MAPT | |
| SCHEMBL6781977 | 0.64 | BRPF1 (0.48) | PPARGNPC1RAB9AHDAC6MAPT | |
| SCHEMBL6776552 | 0.64 | PPARG (0.48) | PPARGNPC1RAB9AHDAC6SMN1; SMN2 | |
| SCHEMBL7379857 | 0.62 | HDAC6 (0.44) | PPARGNPC1RAB9AHDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000050419-A1 | SUBSTITUTED BICYCLIC HETEROCYCLES AND THE USE THEREOF AS THROMBIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-08-31 | — | — | WO | disclosed |