Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419268 | 0.82 | ALDH1A1 (0.45) | FFAR4PKMLMNANPSR1ALDH1A1 | |
| SCHEMBL783714 | 0.78 | LMNA (0.59) | PKMLMNANPSR1ALDH1A1KDM4E | |
| SCHEMBL3351014 | 0.78 | LMNA (0.40) | PKMLMNANPSR1ALDH1A1KDM4E | |
| SCHEMBL7408562 | 0.76 | KDM4E (0.37) | FFAR4ALDH1A1KDM4EHTTATM | |
| SCHEMBL2548565 | 0.75 | LMNA (0.44) | PKMLMNANPSR1ALDH1A1KDM4E | |
| SCHEMBL7415923 | 0.75 | KDM4E (0.36) | FFAR4PKMLMNAALDH1A1KDM4E | |
| SCHEMBL2465485 | 0.74 | PARP1 (0.38) | FFAR4ALDH1A1KDM4EHTTATM | |
| SCHEMBL2465219 | 0.74 | AKR1C4 (0.38) | FFAR4ALDH1A1KDM4EHTTATM | |
| SCHEMBL7332583 | 0.73 | LMNA (0.42) | PKMLMNANPSR1ALDH1A1KDM4E | |
| SCHEMBL672668 | 0.72 | LMNA (0.44) | PKMLMNANPSR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991016888-A1 | SPIRO[BENZOFURANCYCLOALKANE]CARBOXAMIDES AS 5HT3 ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-11-14 | — | — | WO | disclosed |