Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | STK25 | O00506 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449996 | 0.86 | ALOX15 (0.38) | PRKCIGAAHDAC1HDAC2HDAC3 | |
| SCHEMBL7413823 | 0.86 | ALOX15 (0.38) | PRKCIGAAHDAC1HDAC2HDAC3 | |
| SCHEMBL7979459 | 0.83 | HCAR3 (0.47) | RAB9ANPC1PKMHTTMAPT | |
| SCHEMBL7476265 | 0.74 | ALOX15 (0.36) | PRKCIRAB9ANPC1PKML3MBTL1 | |
| SCHEMBL7100641 | 0.73 | AAK1 (0.38) | PRKCIRAB9ANPC1PKML3MBTL1 | |
| SCHEMBL7097430 | 0.73 | ALOX15 (0.35) | PRKCIRAB9ANPC1PKML3MBTL1 | |
| SCHEMBL7977952 | 0.72 | LMNA (0.45) | GAARAB9AL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL7421332 | 0.71 | PRKCI (0.33) | PRKCIGAARAB9ANPC1PKM | |
| SCHEMBL7421339 | 0.71 | PRKCI (0.32) | PRKCIGAARAB9ANPC1PKM | |
| SCHEMBL7099917 | 0.71 | STK25 (0.32) | PRKCIHDAC1HDAC2HDAC3STK25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |