Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.37 |
| ▸ | MICA | Q29983 | 2/20 | 0.37 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421439 | 0.84 | HCAR3 (0.40) | CTSKCTSSKLRK1MICARAET1L | |
| SCHEMBL16379880 | 0.79 | CTSK (0.43) | CTSKCTSSKLRK1MICARAET1L | |
| SCHEMBL21468963 | 0.79 | CTSK (0.43) | CTSKCTSSKLRK1MICARAET1L | |
| SCHEMBL22617062 | 0.78 | MEN1 (0.46) | CTSKCTSSCTSLCTSB | |
| SCHEMBL20434046 | 0.78 | CTSS (0.55) | CTSKCTSSKLRK1MICARAET1L | |
| SCHEMBL5445090 | 0.77 | CTSS (0.54) | CTSKCTSSKLRK1MICARAET1L | |
| SCHEMBL5443088 | 0.77 | CTSS (0.54) | CTSKCTSSKLRK1MICARAET1L | |
| SCHEMBL7413823 | 0.75 | ALOX15 (0.38) | AAK1PRKCI | |
| SCHEMBL4449996 | 0.75 | ALOX15 (0.38) | AAK1PRKCI | |
| SCHEMBL7420037 | 0.75 | ALDH1A1 (0.37) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |