Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 4/20 | 0.53 |
| ▸ | PYGL | P06737 | 4/20 | 0.40 |
| ▸ | PYGM | P11217 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419284 | 0.86 | AADAT (0.40) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL10207849 | 0.86 | BACE1 (0.41) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL7418053 | 0.84 | AADAT (0.38) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL10036781 | 0.83 | AADAT (0.37) | AADATNFKB1NFKB2RELAKYAT1 | |
| SCHEMBL9886278 | 0.83 | DRD2 (0.46) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL6763198 | 0.83 | AADAT (0.49) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL7424083 | 0.80 | HTT (0.50) | PYGLCCKBR | |
| SCHEMBL9886179 | 0.80 | KYAT1 (0.44) | AADATPYGLPYGMKYAT1KYAT3 | |
| SCHEMBL7848691 | 0.80 | XIAP (0.46) | PYGLCCKBRSCN9A | |
| SCHEMBL9886290 | 0.78 | AADAT (0.43) | AADATPYGLPYGMKYAT1KYAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |