Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421691 | 0.86 | CCKBR (0.51) | CCKBR | |
| SCHEMBL7418053 | 0.82 | AADAT (0.38) | CCKBRPYGL | |
| SCHEMBL7414589 | 0.80 | AADAT (0.53) | CCKBRPYGL | |
| SCHEMBL7848691 | 0.80 | XIAP (0.46) | CCKBRPYGLALDH1A1 | |
| SCHEMBL7419284 | 0.79 | AADAT (0.40) | CCKBRPYGL | |
| SCHEMBL7568437 | 0.78 | CCKBR (0.46) | CCKBR | |
| SCHEMBL8888599 | 0.78 | CCKBR (0.49) | CCKBRPYGL | |
| SCHEMBL10499355 | 0.78 | CCKBR (0.46) | CCKBR | |
| SCHEMBL7598390 | 0.78 | CCKBR (0.63) | CCKBR | |
| SCHEMBL7564700 | 0.78 | CCKBR (0.63) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |