Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 6/20 | 0.39 |
| ▸ | PYGM | P11217 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418053 | 0.88 | AADAT (0.38) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL23119152 | 0.88 | GAA (0.38) | PYGLPYGMNFKB1NFKB2RELA | |
| SCHEMBL7423564 | 0.87 | KYAT1 (0.46) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL7414589 | 0.86 | AADAT (0.53) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL9974770 | 0.84 | LIPG (0.39) | PYGLPYGMSCN9A | |
| SCHEMBL9974767 | 0.81 | DRD2 (0.37) | AADATPYGLPYGMNFKB1NFKB2 | |
| SCHEMBL7424083 | 0.79 | HTT (0.50) | PYGLCCKBR | |
| SCHEMBL23119153 | 0.78 | NPY1R (0.45) | CCKBRSCN9A | |
| SCHEMBL7848691 | 0.78 | XIAP (0.46) | PYGLCCKBRSCN9A | |
| SCHEMBL24190214 | 0.78 | GAA (0.38) | NFKB1NFKB2RELAGAAKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |