SCHEMBL7414724

SCHEMBL7414724

N#CN(C(=N)N)c1ccon1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.31
KCNA5 P22460 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854244 0.69 KMT2A (0.31)
SCHEMBL11569306 0.62 TRPM8 (0.36) KCNN4KCNA5
SCHEMBL2378818 0.62 LMNA (0.41)
SCHEMBL19371437 0.61 POLB (0.44) KCNN4KCNA5
SCHEMBL2418864 0.60 ALDH1A1 (0.36)
Hydrochloric Acid SCHEMBL27083207 0.59
SCHEMBL2379010 0.59 SIGMAR1 (0.47)
SCHEMBL11019871 0.59 KLK1 (0.31)
SCHEMBL19371450 0.58 C1S (0.44)
SCHEMBL1822348 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0979226-A1 ISOXAZOLE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-02-16 EP disclosed
WO-1998047880-A1 ISOXAZOLE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-10-29 WO disclosed