Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 7/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 3/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423470 | 0.88 | F2 (0.41) | — | |
| SCHEMBL7277260 | 0.86 | CASP1 (0.41) | KMT2AMEN1CASP1CASP3CASP8 | |
| SCHEMBL7286995 | 0.84 | CASP1 (0.40) | KMT2AMEN1CASP1CASP3CASP8 | |
| SCHEMBL7417508 | 0.84 | CASP1 (0.35) | CASP1CASP3CASP8CASP7 | |
| SCHEMBL7285059 | 0.83 | CASP3 (0.44) | CASP1CASP3CASP8CASP7 | |
| SCHEMBL7416641 | 0.81 | CASP1 (0.34) | MMP8CASP1CASP3CASP8CASP7 | |
| SCHEMBL7424734 | 0.81 | ERAP2 (0.36) | MMP8 | |
| SCHEMBL7277122 | 0.81 | CASP1 (0.51) | CASP1IL1B | |
| SCHEMBL7277381 | 0.79 | CASP1 (0.58) | CASP1CASP3 | |
| SCHEMBL7301728 | 0.78 | CTSC (0.47) | KMT2AMEN1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014777-A1 | PEPTIDYL DERIVATIVES AS INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | MERCK & CO., INC. (US) | 1993-08-05 | — | — | WO | disclosed |