Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12881314 | 0.88 | L3MBTL3 (0.48) | HRH3KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL12881322 | 0.84 | ACHE (0.51) | HRH3KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL8149861 | 0.84 | MEN1 (0.66) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL20885121 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4075003 | 0.81 | ALDH1A1 (0.52) | HRH3KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL27528589 | 0.80 | ITGB3 (0.60) | HRH3KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL15932473 | 0.76 | ALDH1A1 (0.46) | HRH3KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL1520620 | 0.74 | ATM (0.65) | KDM4EALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL65329 | 0.74 | HRH3 (0.47) | HRH3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL13180491 | 0.74 | GNAI3 (0.57) | KDM4EALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022313-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |