Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 10/20 | 0.47 |
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | CASR | P41180 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936242 | 0.82 | BCAT2 (0.43) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL2726416 | 0.80 | MTNR1A (0.72) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL9536355 | 0.79 | MEN1 (0.48) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL6465218 | 0.79 | LMNA (0.57) | — | |
| SCHEMBL28053814 | 0.79 | CYP2D6 (0.42) | — | |
| SCHEMBL3510106 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL30937427 | 0.77 | CYP2D6 (0.46) | — | |
| SCHEMBL13513553 | 0.76 | TRPA1 (0.44) | MTNR1AMTNR1B | |
| SCHEMBL1426449 | 0.75 | MTNR1A (0.56) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL3505478 | 0.75 | MTNR1A (0.51) | MTNR1AMTNR1BCNR1CNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |