Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408231 | 0.76 | SLC6A1 (0.36) | — | |
| SCHEMBL7412750 | 0.75 | CGAS (0.44) | NR1H3NR1H2CGASMEN1KMT2A | |
| SCHEMBL7410316 | 0.69 | HTR1F (0.40) | — | |
| SCHEMBL7413500 | 0.68 | SIRT1 (0.50) | NR1H3NR1H2MEN1KMT2A | |
| SCHEMBL7408845 | 0.66 | CYP2C9 (0.40) | PRMT5 | |
| SCHEMBL7993233 | 0.65 | CES2 (0.50) | MEN1KMT2A | |
| SCHEMBL7408465 | 0.64 | KMT2A (0.47) | MEN1KMT2A | |
| SCHEMBL7409033 | 0.64 | GAA (0.39) | PRMT5 | |
| SCHEMBL7408135 | 0.63 | SSTR3 (0.39) | MEN1KMT2A | |
| SCHEMBL7407777 | 0.63 | NR2E1 (0.53) | PRMT5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |