Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | MMP7 | P09237 | 2/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219500 | 0.78 | ADAM17 (0.83) | MMP3MMP7ADAMTS4ADAM17ADAMTS1 | |
| SCHEMBL1756728 | 0.77 | CCR1 (0.51) | MMP3MMP7ADAMTS4ADAM17ADAMTS1 | |
| SCHEMBL8947296 | 0.70 | MMP1 (0.68) | ALDH1A1MMP1MMP13MMP2LMNA | |
| SCHEMBL16839693 | 0.69 | CTSC (0.42) | MMP3ALDH1A1MMP1MMP13MMP2 | |
| SCHEMBL30090979 | 0.69 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL21198730 | 0.68 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1CCR1LMNACYP1A2 | |
| SCHEMBL1728532 | 0.68 | ERCC5 (0.68) | MMP1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL1187191 | 0.68 | ADRB2 (0.49) | ADAM17L3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL14351239 | 0.66 | ANO1 (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19ANO1 | |
| SCHEMBL28761123 | 0.66 | PARP10 (0.59) | MMP1MMP13MMP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171422-A1 | MMP INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063165-A1 | MMP INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-26 | — | — | WO | disclosed |