Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.42 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17395959 | 0.83 | FOLH1 (0.69) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL4735612 | 0.82 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7134588 | 0.82 | TSHR (0.54) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL14899751 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL6555382 | 0.80 | MAPT (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL2356669 | 0.80 | FOLH1 (0.70) | KDM4EALDH1A1MAPTTSHRHPGD | |
| SCHEMBL405123 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL619877 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL162322 | 0.80 | MAPT (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| Benzene SCHEMBL1931924 | 0.80 | FOLH1 (0.70) | KDM4EALDH1A1MAPTTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105165823-A | Enhanced Retention Capabilities Through Methods Comprising Surface Treatment Of Functional Particulate Carrier Materials, And Functional Particulate Carrier Materials Made Therefrom | WORLD MINERALS INC | 2015-12-23 | — | — | CN | disclosed |
| US-5733905-A | CONGESTIVE HEART FAILURE; KIDNEY DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1998-03-31 | — | — | US | disclosed |