Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | KYNU | Q16719 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414045 | 0.92 | CTSK (0.51) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL7975561 | 0.84 | CASP1 (0.55) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL7418995 | 0.84 | CTSL (0.51) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL3414548 | 0.84 | CTSK (0.51) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL2342652 | 0.84 | CTSK (0.51) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL25287033 | 0.83 | ALDH1A1 (0.55) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL345953 | 0.83 | PPARA (0.55) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL18686856 | 0.83 | ALDH1A1 (0.55) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL4405472 | 0.82 | ALDH1A1 (0.57) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL4405476 | 0.82 | ALDH1A1 (0.57) | CTSKCTSLCTSSCTSBCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |