Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422853 | 0.86 | THRB (0.44) | MAPTMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4445863 | 0.82 | HCAR3 (0.50) | HCAR3KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL30485017 | 0.72 | PKM (0.57) | KMT2AMAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL2014294 | 0.71 | POLB (0.42) | MAPTMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4443935 | 0.70 | HCAR3 (0.41) | HCAR3KMT2AMAPTMAPK1LMNA | |
| SCHEMBL7412611 | 0.70 | HCAR3 (0.41) | HCAR3KMT2AMAPTMAPK1LMNA | |
| SCHEMBL16654381 | 0.70 | SMN1; SMN2 (0.56) | KMT2AMAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL7979459 | 0.69 | HCAR3 (0.47) | HCAR3KMT2AMAPTMAPK1LMNA | |
| SCHEMBL30196334 | 0.69 | MAPT (0.48) | KMT2AMAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL27508285 | 0.68 | ALDH1A1 (0.48) | HCAR3KMT2AMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244636-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | Boehringer Ingelheim Pharma KG (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047896-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |