Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416926 | 0.85 | MAPT (0.50) | MAPTNPC1KMT2AMEN1HCAR3 | |
| SCHEMBL7415701 | 0.82 | HDAC1 (0.41) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8026140 | 0.80 | MEN1 (0.53) | MAPTNPC1KMT2AMEN1HCAR3 | |
| SCHEMBL7419156 | 0.78 | MAPT (0.39) | MAPTNPC1KMT2AMEN1HCAR3 | |
| SCHEMBL7412060 | 0.78 | MAPT (0.55) | MAPTKMT2AMEN1POLBHTT | |
| SCHEMBL7412565 | 0.78 | HCAR3 (0.57) | MAPTHCAR3POLBCDC25BHTT | |
| SCHEMBL7424865 | 0.72 | HCAR3 (0.53) | MAPTKMT2AMEN1HCAR3POLB | |
| SCHEMBL7410714 | 0.72 | HCAR3 (0.47) | MAPTKMT2AHCAR3CDC25BHTT | |
| SCHEMBL7412123 | 0.72 | HSD11B1 (0.48) | MAPTKMT2AMEN1HCAR3POLB | |
| SCHEMBL7416558 | 0.71 | ALDH1A1 (0.53) | KMT2AHCAR3ALDH1A1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152866-C | Benzimidazoles, production thereof and use thereof medicaments | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-06-09 | — | — | CN | disclosed |
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| CN-1308614-A | Benzimidazoles, production thereof and use thereof medicaments | BOEHRINGER INGELHEIM PHAMA KG (DE) | 2001-08-15 | — | — | CN | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |