Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 13/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417403 | 0.90 | STS (0.51) | TGFBR1GPR119HTR6LIMK2BCHE | |
| SCHEMBL7416856 | 0.89 | GPR119 (0.49) | TGFBR1GPR119HTR6 | |
| SCHEMBL7413311 | 0.88 | GPR119 (0.46) | TGFBR1GPR119HTR6LIMK2BCHE | |
| SCHEMBL7415441 | 0.88 | GPR119 (0.47) | TGFBR1GPR119HTR6LIMK2 | |
| SCHEMBL7413671 | 0.86 | STS (0.50) | TGFBR1GPR119HTR6LIMK2 | |
| SCHEMBL7415294 | 0.84 | GPR119 (0.53) | TGFBR1GPR119HTR6 | |
| SCHEMBL7416559 | 0.84 | YAP1 (0.44) | GPR119HTR6BCHE | |
| SCHEMBL7416512 | 0.83 | STS (0.52) | TGFBR1GPR119HTR6LIMK2 | |
| SCHEMBL7467827 | 0.83 | GPR119 (0.50) | TGFBR1GPR119HTR6 | |
| SCHEMBL7418854 | 0.82 | GPR119 (0.47) | TGFBR1GPR119HTR6LIMK2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880136-A | PREVENTING THROMBUS FORMATION | MERCK & CO., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5814643-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-09-29 | — | — | US | disclosed |