Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417427 | 0.88 | TGFBR1 (0.52) | GPR119TGFBR1HTR6LIMK2 | |
| SCHEMBL7416856 | 0.86 | GPR119 (0.49) | GPR119TGFBR1HTR6SCN9A | |
| SCHEMBL7417403 | 0.84 | STS (0.51) | GPR119TGFBR1HTR6ITGB3ITGA2B | |
| SCHEMBL7413311 | 0.84 | GPR119 (0.46) | GPR119TGFBR1HTR6SCN9ALIMK2 | |
| SCHEMBL7415294 | 0.81 | GPR119 (0.53) | GPR119TGFBR1HTR6SCN9A | |
| SCHEMBL7467827 | 0.81 | GPR119 (0.50) | GPR119TGFBR1HTR6SCN9A | |
| SCHEMBL7413671 | 0.81 | STS (0.50) | GPR119TGFBR1HTR6ITGB3ITGA2B | |
| SCHEMBL7416559 | 0.78 | YAP1 (0.44) | GPR119HTR6ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7409715 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7416512 | 0.78 | STS (0.52) | GPR119TGFBR1HTR6SCN9AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880136-A | PREVENTING THROMBUS FORMATION | MERCK & CO., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5814643-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-09-29 | — | — | US | disclosed |