Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428686 | 0.95 | CTSK (0.56) | CTSKMAPTRARARARBRARG | |
| SCHEMBL7421947 | 0.93 | CTSK (0.56) | CTSKMAPTRARARARBRARG | |
| SCHEMBL1655302 | 0.90 | CTSK (0.62) | CTSKMAPTLDHALDHBSMN1; SMN2 | |
| SCHEMBL4717602 | 0.87 | CTSK (0.64) | CTSKMAPTRARARARBRARG | |
| SCHEMBL7425252 | 0.84 | CTSK (0.54) | CTSKMAPTCDC7DBF4LDHA | |
| SCHEMBL7426736 | 0.81 | CTSK (0.48) | CTSKMAPTLDHALDHBSMN1; SMN2 | |
| SCHEMBL4713366 | 0.79 | CTSK (0.70) | CTSKMAPTLDHALDHBSMN1; SMN2 | |
| SCHEMBL16746841 | 0.79 | CTSK (0.51) | CTSKMAPTRARARARBRARG | |
| SCHEMBL7422285 | 0.78 | CTSK (0.47) | CTSKMAPTLDHALDHBSMN1; SMN2 | |
| SCHEMBL7420772 | 0.77 | ALDH1A1 (0.51) | CTSKMAPTSMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |