Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.50 |
| ▸ | CPS1 | P31327 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423445 | 0.94 | KDM2B (0.50) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4841620 | 0.94 | CPS1 (0.52) | KDM2BCPS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4131191 | 0.87 | ALDH1A1 (0.53) | KDM2BCPS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1340897 | 0.82 | NOS2 (0.48) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4115692 | 0.82 | KDM2B (0.47) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14477305 | 0.82 | KDM2B (0.50) | KDM2BCPS1ALDH1A1MEN1KMT2A | |
| SCHEMBL4113759 | 0.82 | MAPT (0.61) | KDM2BCPS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL16163091 | 0.81 | POLB (0.61) | KDM2BCPS1ALDH1A1MEN1KMT2A | |
| SCHEMBL5280460 | 0.81 | KDM2B (0.49) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1942608 | 0.81 | CPS1 (0.70) | KDM2BCPS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423030-B2 | 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof | SANOFI-AVENTIS (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20070099895-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099895-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | CYP11B2, CYP11B1, GOT2 | KDM2B 2966/4885CPS1 180/4885SMN1; SMN2 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.