Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.50 |
| ▸ | CPS1 | P31327 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839335 | 0.94 | KDM2B (0.50) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4841620 | 0.88 | CPS1 (0.52) | KDM2BCPS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14477305 | 0.82 | KDM2B (0.50) | KDM2BCPS1ALDH1A1MEN1KMT2A | |
| SCHEMBL1340897 | 0.82 | NOS2 (0.48) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4113759 | 0.82 | MAPT (0.61) | KDM2BCPS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4115692 | 0.82 | KDM2B (0.47) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4131191 | 0.81 | ALDH1A1 (0.53) | KDM2BCPS1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30514010 | 0.81 | CPS1 (0.70) | KDM2BCPS1MEN1KMT2A | |
| SCHEMBL16163091 | 0.81 | POLB (0.61) | KDM2BCPS1ALDH1A1MEN1KMT2A | |
| SCHEMBL5280460 | 0.81 | KDM2B (0.49) | KDM2BCPS1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |