Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367841 | 0.83 | CTSS (0.48) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7419026 | 0.71 | LONP1 (0.42) | CTSLCTSSCTSBCTSKCPB2 | |
| SCHEMBL7417521 | 0.70 | CTSS (0.38) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7422882 | 0.70 | CTSS (0.38) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7012870 | 0.69 | CTSS (0.41) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5363187 | 0.68 | CTSS (0.39) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7008282 | 0.68 | CTSL (0.40) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7536451 | 0.67 | LONP1 (0.41) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7417783 | 0.66 | CTSS (0.42) | CTSLCTSSCTSBCTSKCPB2 | |
| SCHEMBL7007715 | 0.66 | CTSS (0.39) | CTSLCTSSCTSBCTSKCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |