Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EEF2K | O00418 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 10/20 | 0.50 |
| ▸ | MMP9 | P14780 | 7/20 | 0.50 |
| ▸ | MMP3 | P08254 | 6/20 | 0.50 |
| ▸ | MMP1 | P03956 | 6/20 | 0.50 |
| ▸ | MMP13 | P45452 | 6/20 | 0.50 |
| ▸ | MMP7 | P09237 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454202 | 0.89 | MMP9 (0.58) | ATML3MBTL1ALDH1A1EEF2KMMP2 | |
| SCHEMBL7410702 | 0.85 | PDE4A (0.67) | ATML3MBTL1ALDH1A1EEF2KMMP2 | |
| SCHEMBL3199799 | 0.83 | ALDH1A1 (0.52) | ATML3MBTL1ALDH1A1EEF2KMMP2 | |
| SCHEMBL7419745 | 0.81 | MMP1 (0.59) | ATML3MBTL1ALDH1A1EEF2KMMP2 | |
| SCHEMBL28404274 | 0.78 | ATM (0.76) | ATML3MBTL1ALDH1A1EEF2KKMT2A | |
| SCHEMBL7473660 | 0.77 | SLC1A3 (0.55) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7418100 | 0.77 | MMP2 (0.55) | ALDH1A1MMP2MMP9MMP3MMP1 | |
| SCHEMBL14242038 | 0.75 | EGFR (0.51) | ATML3MBTL1ALDH1A1EEF2KKMT2A | |
| SCHEMBL14242036 | 0.75 | EGFR (0.51) | ATML3MBTL1ALDH1A1EEF2KKMT2A | |
| SCHEMBL7572130 | 0.75 | ATM (0.76) | ATML3MBTL1ALDH1A1EEF2KKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |