Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287940 | 0.84 | CD274 (0.47) | RENCTSKALDH1A1 | |
| SCHEMBL9286028 | 0.82 | ALDH1A1 (0.47) | RENALDH1A1 | |
| SCHEMBL7412829 | 0.79 | CYP2D6 (0.42) | RENCTSKCYP2D6CTSLCTSB | |
| SCHEMBL15497079 | 0.76 | USP2 (0.50) | L3MBTL1ALDH1A1POLBCTSLCTSB | |
| SCHEMBL9270675 | 0.75 | CTSL (0.40) | RENCTSKCYP2D6CTSLCTSB | |
| SCHEMBL7376568 | 0.75 | REN (0.38) | RENCTSKCYP2D6CTSLCTSB | |
| SCHEMBL9263938 | 0.74 | CYP2D6 (0.42) | RENCTSKCYP2D6CTSLCTSB | |
| SCHEMBL16252561 | 0.72 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL7345146 | 0.71 | CYP2D6 (0.48) | CTSKCYP2D6CTSLCTSBCTSS | |
| SCHEMBL7344748 | 0.69 | CYP2D6 (0.38) | RENCTSKCYP2D6CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003429-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |