Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565765 | 0.73 | MEN1 (0.44) | KMT2AMEN1NPC1SIGMAR1 | |
| SCHEMBL7698345 | 0.68 | KMT2A (0.34) | KMT2AMEN1NPC1DRD1EDNRA | |
| SCHEMBL6716278 | 0.67 | MTNR1A (0.34) | KMT2AMEN1NPC1DRD1TDP1 | |
| SCHEMBL8570815 | 0.66 | SIGMAR1 (0.40) | KMT2AMEN1SIGMAR1 | |
| SCHEMBL14113763 | 0.66 | ALDH1A1 (0.38) | KMT2AMEN1NPC1DRD1ALDH1A1 | |
| SCHEMBL13453317 | 0.65 | ALDH1A1 (0.50) | KMT2AMEN1NPC1DRD1ALDH1A1 | |
| SCHEMBL22779306 | 0.65 | ALDH1A1 (0.36) | KMT2AMEN1NPC1DRD1ALDH1A1 | |
| SCHEMBL22952568 | 0.65 | ALDH1A1 (0.36) | KMT2AMEN1NPC1DRD1ALDH1A1 | |
| SCHEMBL2679605 | 0.65 | ALDH1A1 (0.36) | KMT2AMEN1NPC1DRD1ALDH1A1 | |
| SCHEMBL8144693 | 0.65 | HTR2A (0.41) | KMT2AMEN1NPC1DRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-A1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | Akzo Nobel N.V. (NL) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007978-A1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL N.V. (NL) | 2000-02-17 | — | — | WO | disclosed |