Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703390 | 0.77 | MTNR1A (0.54) | EDNRAGAAMTNR1AMTNR1B | |
| SCHEMBL7413569 | 0.76 | LTB4R (0.41) | EDNRASLC6A2SLC6A4NPC1 | |
| SCHEMBL7698344 | 0.75 | IDO1 (0.40) | KMT2AMITFTDP1ALDH1A1EDNRA | |
| SCHEMBL7419856 | 0.68 | KMT2A (0.40) | KMT2AMITFTDP1ALDH1A1EDNRA | |
| SCHEMBL7704449 | 0.68 | SLC6A9 (0.65) | MTNR1AMTNR1B | |
| SCHEMBL6716278 | 0.65 | MTNR1A (0.34) | KMT2AMITFTDP1MTNR1AMTNR1B | |
| SCHEMBL12187737 | 0.64 | KMT2A (0.64) | KMT2A | |
| SCHEMBL9348463 | 0.64 | SLC6A2 (0.35) | KMT2AALDH1A1EDNRASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL18981946 | 0.63 | KMT2A (0.62) | KMT2A | |
| SCHEMBL14916471 | 0.61 | ALDH1A1 (0.54) | KMT2AALDH1A1GAAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |