Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421892 | 0.94 | NR4A2 (0.51) | LTB4RLTB4R2ALOX5NR4A2MAOB | |
| SCHEMBL7424454 | 0.92 | NR4A2 (0.49) | LTB4RLTB4R2ALOX5NR4A2PTGES | |
| SCHEMBL6834465 | 0.89 | LTB4R (0.45) | LTB4RLTB4R2ALOX5PTGESMAOB | |
| SCHEMBL7424617 | 0.89 | MAOB (0.42) | LTB4RLTB4R2ALOX5NR4A2MAOB | |
| SCHEMBL7427123 | 0.88 | LTB4R (0.44) | LTB4RLTB4R2ALOX5NR4A2PTGES | |
| SCHEMBL7424281 | 0.86 | NR4A2 (0.49) | LTB4RLTB4R2ALOX5NR4A2PTGES | |
| SCHEMBL7426641 | 0.86 | LTB4R (0.47) | LTB4RLTB4R2ALOX5PTGESCYP2D6 | |
| SCHEMBL7420337 | 0.85 | FAAH (0.42) | LTB4RLTB4R2ALOX5PTGESCYP2D6 | |
| SCHEMBL7430634 | 0.84 | AOC3 (0.39) | — | |
| SCHEMBL7426730 | 0.82 | AOC3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |