Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 8/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 16/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425834 | 0.92 | MMP2 (0.47) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL7475365 | 0.91 | MMP3 (0.45) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL8664026 | 0.72 | MMP1 (0.51) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL8652197 | 0.71 | MMP1 (0.49) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL7192046 | 0.70 | MMP3 (0.52) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL8887821 | 0.67 | MMP1 (0.76) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL8899210 | 0.67 | MMP1 (0.76) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL8026514 | 0.67 | MMP1 (0.76) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL7411762 | 0.66 | MMP1 (0.58) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL14282131 | 0.65 | MMP1 (0.50) | MMP3MMP1MMP9MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944587-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2002-03-20 | — | — | EP | disclosed |
| EP-0944587-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998024759-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |