Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.45 |
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 12/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420144 | 0.91 | MMP3 (0.48) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL7425834 | 0.88 | MMP2 (0.47) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL7474091 | 0.77 | GRIK1 (0.46) | MMP3MMP1MMP9MMP2 | |
| SCHEMBL7471920 | 0.70 | MMP2 (0.37) | MMP3MMP1MMP9MMP2 | |
| SCHEMBL8664026 | 0.69 | MMP1 (0.51) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL7192046 | 0.69 | MMP3 (0.52) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL8652197 | 0.68 | MMP1 (0.49) | MMP3MMP1MMP9MMP2MMP7 | |
| SCHEMBL28611674 | 0.66 | LMNA (0.41) | MEN1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6892615 | 0.64 | CTSS (0.61) | MMP1 | |
| SCHEMBL8887821 | 0.64 | MMP1 (0.76) | MMP3MMP1MMP9MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944587-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2002-03-20 | — | — | EP | disclosed |
| EP-0944587-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998024759-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |