Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP9 | P55211 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423871 | 0.89 | L3MBTL1 (0.41) | ACHEHTR1ADRD1ALDH1A1DRD2 | |
| SCHEMBL7307524 | 0.73 | KMT2A (0.44) | ACHEALDH1A1DRD2MAPTMEN1 | |
| SCHEMBL15727806 | 0.73 | HTR1A (0.50) | ACHEHTR1ADRD1ALDH1A1DRD2 | |
| SCHEMBL31537993 | 0.70 | HTR1A (0.44) | ACHEHTR1ADRD1ALDH1A1DRD2 | |
| SCHEMBL7418416 | 0.69 | KDM4E (0.39) | ALDH1A1DRD2MAPTCASP1CASP7 | |
| SCHEMBL1951457 | 0.67 | CYP1A2 (0.46) | ACHEALDH1A1MAPTCASP1CASP3 | |
| SCHEMBL22145710 | 0.65 | DPP7 (0.54) | ALDH1A1DRD2MAPTGAADPP7 | |
| SCHEMBL1295027 | 0.65 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12549292 | 0.65 | SMN1; SMN2 (0.48) | ALDH1A1DRD2MAPT | |
| SCHEMBL7419302 | 0.64 | DPP7 (0.42) | ALDH1A1DRD2MAPTGAASIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602145-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0702671-A4 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1996-06-19 | — | — | EP | disclosed |
| EP-0702671-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029273-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |