Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7307645 | 0.81 | TNF (0.40) | KMT2AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL14558121 | 0.75 | MAPT (0.46) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL14558120 | 0.73 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7420931 | 0.73 | ACHE (0.39) | KMT2AALDH1A1MAPTMEN1DRD2 | |
| SCHEMBL5998428 | 0.73 | DPP7 (0.41) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7423871 | 0.73 | L3MBTL1 (0.41) | ALDH1A1MAPTL3MBTL1DRD2ACHE | |
| SCHEMBL15727806 | 0.73 | HTR1A (0.50) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL1295027 | 0.72 | ALDH1A1 (0.61) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7307062 | 0.71 | MAPT (0.46) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL12549292 | 0.70 | SMN1; SMN2 (0.48) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |