Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422349 | 0.92 | AAK1 (0.43) | CTSLCTSBMMP12LMNAMMP13 | |
| SCHEMBL7415842 | 0.88 | HSD17B10 (0.43) | CTSLCTSBMMP12LMNATDP1 | |
| SCHEMBL7429544 | 0.84 | LMNA (0.45) | CTSLCTSBLMNAALDH1A1POLB | |
| SCHEMBL7426026 | 0.84 | HCAR2 (0.39) | CTSBLMNAKMT2AALDH1A1POLB | |
| SCHEMBL7421321 | 0.82 | NTSR1 (0.40) | LMNAKMT2AALDH1A1POLBHSD17B10 | |
| SCHEMBL7425766 | 0.77 | PSMB5 (0.49) | PSMB5CTSLMMP12GPR88 | |
| SCHEMBL7424092 | 0.77 | PSMB5 (0.49) | PSMB5CTSLMMP12GPR88 | |
| SCHEMBL5870237 | 0.77 | MMP12 (0.44) | PSMB5CTSLCTSBMMP12NAAA | |
| SCHEMBL5870227 | 0.77 | MMP12 (0.44) | PSMB5CTSLCTSBMMP12NAAA | |
| SCHEMBL5870230 | 0.77 | MMP12 (0.44) | PSMB5CTSLCTSBMMP12NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |