Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422349 | 0.92 | AAK1 (0.43) | HSD17B10POLBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7429544 | 0.90 | LMNA (0.45) | HSD17B10POLBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7420933 | 0.88 | PSMB5 (0.46) | HSD17B10POLBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7426026 | 0.86 | HCAR2 (0.39) | HSD17B10POLBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7421321 | 0.85 | NTSR1 (0.40) | HSD17B10POLBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7418968 | 0.80 | CTSK (0.40) | HSD17B10POLBL3MBTL1CTSKCTSL | |
| SCHEMBL7423963 | 0.74 | OPRK1 (0.48) | CTSKCTSLCTSBCTSS | |
| SCHEMBL15251844 | 0.74 | L3MBTL1 (0.41) | HSD17B10POLBL3MBTL1CTSKCTSB | |
| SCHEMBL27853183 | 0.74 | L3MBTL1 (0.41) | HSD17B10POLBL3MBTL1CTSKCTSB | |
| SCHEMBL7697567 | 0.74 | ALDH1A1 (0.45) | HSD17B10POLBALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |