Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 10/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427618 | 0.84 | AADAT (0.40) | PYGLKDM4EALDH1A1 | |
| SCHEMBL7425491 | 0.83 | KDM4E (0.36) | PYGLKDM4EALDH1A1GAA | |
| SCHEMBL7415758 | 0.82 | ACE (0.36) | PYGLKDM4E | |
| SCHEMBL7427520 | 0.79 | PYGL (0.49) | PYGLCACNA1SALDH1A1GAAXIAP | |
| SCHEMBL8889889 | 0.77 | ALDH1A1 (0.35) | PYGLKDM4EALDH1A1GAA | |
| SCHEMBL5628897 | 0.75 | AADAT (0.52) | PYGLCACNA1SKDM4EALDH1A1GAA | |
| SCHEMBL8890894 | 0.74 | ALDH1A1 (0.36) | PYGLKDM4EALDH1A1GAA | |
| SCHEMBL8891676 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1GAA | |
| SCHEMBL4071608 | 0.69 | AADAT (0.48) | PYGLCACNA1SKDM4EALDH1A1GAA | |
| SCHEMBL1270037 | 0.69 | SCN9A (0.52) | XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |