Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420944 | 0.79 | PYGL (0.49) | PYGLXIAPALDH1A1GAACACNA1S | |
| SCHEMBL7427516 | 0.78 | SCN9A (0.39) | XIAPACEMME | |
| Acetic Acid SCHEMBL21402726 | 0.77 | GPBAR1 (0.42) | MAPTALDH1A1ACEGPBAR1GAA | |
| SCHEMBL7422979 | 0.76 | PYGL (0.47) | PYGLXIAPACE | |
| SCHEMBL5628897 | 0.74 | AADAT (0.52) | PYGLALDH1A1GAACACNA1S | |
| SCHEMBL26996407 | 0.74 | MAPT (0.40) | XIAPMAPTALDH1A1GAAMEN1 | |
| SCHEMBL7414939 | 0.73 | SCN9A (0.48) | PYGLXIAPACEMME | |
| SCHEMBL7420278 | 0.72 | CA1 (0.46) | PYGLALDH1A1ACEGAA | |
| SCHEMBL7416731 | 0.72 | PYGL (0.44) | PYGLXIAPACEMME | |
| SCHEMBL22076255 | 0.71 | CTSL (0.55) | MAPTALDH1A1GPBAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |