Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937316 | 0.82 | LMNA (0.47) | LMNAMAPK1KMT2AL3MBTL1BLM | |
| SCHEMBL28722083 | 0.77 | AOC3 (0.33) | LMNATRPA1AOC3SLC6A4 | |
| SCHEMBL7422836 | 0.75 | NAAA (0.40) | LMNAMAPK1TSHRCES2CES1 | |
| SCHEMBL7151189 | 0.75 | SLC6A2 (0.40) | LMNAMAPK1KMT2ABLMHPGD | |
| SCHEMBL275598 | 0.73 | LMNA (0.64) | LMNAMAPK1KMT2AL3MBTL1BLM | |
| SCHEMBL11049262 | 0.72 | ALDH1A1 (0.48) | LMNABLMPOLBHPGDTSHR | |
| SCHEMBL8407813 | 0.71 | LMNA (0.38) | LMNAMAPK1KMT2AL3MBTL1BLM | |
| SCHEMBL503436 | 0.69 | KMT2A (0.55) | LMNAMAPK1KMT2AL3MBTL1BLM | |
| SCHEMBL503435 | 0.69 | KMT2A (0.55) | LMNAMAPK1KMT2AL3MBTL1BLM | |
| SCHEMBL6400516 | 0.69 | KMT2A (0.55) | LMNAMAPK1KMT2AL3MBTL1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773926-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |