Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937316 | 0.77 | LMNA (0.47) | LMNAMAPK1CES2CES1 | |
| SCHEMBL7422236 | 0.75 | LMNA (0.41) | LMNAMAPK1NPC1RAB9ATSHR | |
| SCHEMBL6890650 | 0.71 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1 | |
| SCHEMBL7284382 | 0.71 | CNR2 (0.41) | NAAAHTTTSHRALDH1A1 | |
| SCHEMBL27719983 | 0.71 | ALDH1A1 (0.41) | NAAALMNAMAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL7916115 | 0.70 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL275598 | 0.69 | LMNA (0.64) | LMNAMAPK1TSHRCES2CES1 | |
| SCHEMBL9243840 | 0.69 | HTT (0.44) | NAAAASAH1CYSLTR2CYSLTR1HTT | |
| SCHEMBL9243844 | 0.69 | HTT (0.44) | NAAAASAH1CYSLTR2CYSLTR1HTT | |
| SCHEMBL5570575 | 0.69 | LMNA (0.48) | LMNAMAPK1CYSLTR2CYSLTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773926-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |