Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415336 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL7422874 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL7425099 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL7425089 | 0.78 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EPKMMEN1 | |
| SCHEMBL8687291 | 0.77 | ALDH1A1 (0.51) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL7415330 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BKDM4EPKMYAP1 | |
| SCHEMBL7425094 | 0.75 | ITGB3 (0.48) | ITGB3ITGA2BKDM4EPKMYAP1 | |
| SCHEMBL7415332 | 0.73 | ITGB3 (0.47) | ITGB3ITGA2BKDM4EPKMYAP1 | |
| SCHEMBL7306244 | 0.72 | ITGB3 (0.42) | ITGB3ITGA2BPKMSMN1; SMN2LMNA | |
| SCHEMBL7301488 | 0.71 | ITGB3 (0.43) | ITGB3ITGA2BPKMSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684823-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0684823-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |