Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422876 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL7425099 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EPKMMCHR1 | |
| SCHEMBL7415330 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BKDM4EPKMMCHR1 | |
| SCHEMBL8687291 | 0.82 | ALDH1A1 (0.51) | ITGB3ITGA2BKDM4EPKMFAAH | |
| SCHEMBL7415332 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BKDM4EPKMMCHR1 | |
| SCHEMBL7425089 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EPKMMCHR1 | |
| SCHEMBL7425094 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BKDM4EPKMMCHR1 | |
| SCHEMBL7422874 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL8687096 | 0.74 | GPR119 (0.41) | ITGB3ITGA2BKDM4EPKMFAAH | |
| SCHEMBL7422985 | 0.73 | ITGB3 (0.78) | ITGB3ITGA2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |