Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 7/20 | 0.37 |
| ▸ | CA1 | P00915 | 7/20 | 0.37 |
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA9 | Q16790 | 7/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | GCKR | Q14397 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425364 | 0.78 | HDAC3 (0.49) | HSD17B1HSD17B2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27503318 | 0.77 | HDAC3 (0.47) | HSD17B1HSD17B2CA12CA1CA2 | |
| SCHEMBL2633939 | 0.72 | POLB (0.52) | CA1CA2PFKFB3MAPTALDH1A1 | |
| SCHEMBL3055723 | 0.72 | KDM4E (0.60) | PFKFB3MAPTRXFP1ALDH1A1POLB | |
| SCHEMBL7421349 | 0.72 | KDM4E (0.47) | CA12CA1CA2CA9PFKFB3 | |
| SCHEMBL9198944 | 0.71 | L3MBTL1 (0.34) | CA12CA1CA2CA9PFKFB3 | |
| SCHEMBL5727547 | 0.71 | HSD17B1 (0.51) | HSD17B1HSD17B2MAPTSNCA | |
| SCHEMBL5727190 | 0.71 | ADAMTS5 (0.51) | HSD17B1HSD17B2POLB | |
| SCHEMBL7425945 | 0.71 | MKNK1 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3046411 | 0.71 | RAB9A (0.47) | HSD17B1HSD17B2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894088-A4 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0894088-A1 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1998024784-A1 | SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-11 | — | — | WO | disclosed |