Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420278 | 0.87 | CA1 (0.46) | PYGLCA1CA2ACHEACE | |
| SCHEMBL7416731 | 0.86 | PYGL (0.44) | PYGLCA1CA2ACHEXIAP | |
| SCHEMBL7414939 | 0.83 | SCN9A (0.48) | PYGLXIAPACE | |
| SCHEMBL7427476 | 0.82 | ACE (0.46) | CA1CA2ACHEACEPREP | |
| SCHEMBL9199408 | 0.82 | ACE (0.44) | CA1CA2ACHEXIAPACE | |
| SCHEMBL22076255 | 0.80 | CTSL (0.55) | CTSLNAAA | |
| SCHEMBL7425217 | 0.80 | ACE (0.45) | CA1CA2ACHEXIAPACE | |
| SCHEMBL7418419 | 0.79 | CCKBR (0.53) | — | |
| SCHEMBL7427520 | 0.76 | PYGL (0.49) | PYGLXIAPACE | |
| SCHEMBL7420876 | 0.75 | CA1 (0.49) | CA1CA2ACHEPREPNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |