Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.78 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.78 |
| ▸ | MMP13 | P45452 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422991 | 1.00 | ITGB3 (0.78) | ITGB3ITGA2BMMP13TP53LMNA | |
| SCHEMBL609722 | 0.88 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL6441257 | 0.82 | ITGB3 (0.75) | ITGB3ITGA2BTP53LMNA | |
| SCHEMBL7415330 | 0.78 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7425089 | 0.77 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7422874 | 0.76 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7425099 | 0.75 | ITGB3 (0.53) | ITGB3ITGA2BTP53 | |
| SCHEMBL7425094 | 0.74 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL7415336 | 0.73 | ITGB3 (0.53) | ITGB3ITGA2BTP53 | |
| SCHEMBL8687291 | 0.73 | ALDH1A1 (0.51) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |