Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609722 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7422985 | 0.82 | ITGB3 (0.78) | ITGB3ITGA2BLMNATP53 | |
| SCHEMBL7422991 | 0.82 | ITGB3 (0.78) | ITGB3ITGA2BLMNATP53 | |
| SCHEMBL7842910 | 0.74 | LMNA (0.56) | ITGB3ITGA2BLMNATP53SMN1; SMN2 | |
| SCHEMBL24130567 | 0.63 | ALDH1A1 (0.63) | — | |
| SCHEMBL9877830 | 0.63 | ALDH1A1 (0.63) | — | |
| SCHEMBL7397488 | 0.62 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL3823886 | 0.62 | L3MBTL1 (0.58) | TP53SMN1; SMN2 | |
| SCHEMBL11351046 | 0.61 | MMP9 (0.71) | — | |
| SCHEMBL7066619 | 0.61 | MMP9 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050142162-A1 | Soft tissue implants and anti-scarring agents | ANGIOTECH INTERNATIONAL AG (CH) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050142162-A1 | Soft tissue implants and anti-scarring agents | MMP1, COL2A1, FN1 | ITGB3 625/4885ITGA2B 928/4885LMNA 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.